On September 14, 2012 we successfully implanted the bioprosthetic Melody valve in a 28 year old female patient who was suffering from severe pulmonary valve insufficiency (conduit failure). The patient was considered of very high surgical risk due to multiple (7) previous surgeries. Despite patient’s complex anatomy that needed special manipulations, and after 7 hours of efforts, the valve was finally in place. Echocardiography post-procedure showed very good valve function. The patient had no complications and was discharged 2 days post-procedure. At 2-week follow-up she is feeling well, and has returned to work.